Thorne 5-Hydroxytryptophan -- 90 Capsules

Thorne 5-Hydroxytryptophan Description Enhances Sleep and Helps Manage Stress Mood Sleep Gluten Free Dairy Free Soy Free 5-HTP increases serotonin levels to promote restful sleep, manage stress, and decrease sugar cravings. It contains pyridoxal-5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.   The serotonin levels in the body are associated with the regulation of sleep, mood, and appetite. A balanced serotonin level has been shown to support restful sleep, good mood, and decreased sugar cravings. There are several ways to support a healthy serotonin level. L-tryptophan and 5-Hydroxytryptophan (5-HTP) are both precursors to serotonin. However, supplementation with 5-HTP is preferable, because unlike L-tryptophan, 5-HTP cannot be shunted into other uses in the body, such as niacin or protein production. 5-HTP is well absorbed by the body and easily crosses the blood-brain barrier where it can increase the synthesis of serotonin in the central nervous system. And 5-HTP can be taken with meals without reducing its effectiveness.   5-Hydroxytryptophan (5-HTP) is the intermediate metabolite the body produces when it initiates the process of converting the essential amino acid L-tryptophan to serotonin. Therefore, supplementation with 5-HTP will bypass the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase – which is the rate-limiting step in the synthesis of serotonin – and is a conversion that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron. 5-HTP is well absorbed when taken orally, with about 70 percent going into the bloodstream. Intestinal absorption of 5-HTP does not require the presence of a transport molecule, and its absorption is not affected by the presence of other amino acids; therefore, 5-HTP can be taken with meals without reducing its effectiveness. 5-HTP has been shown to have a beneficial impact on mood, sleep, carbohydrate cravings, and discomfort associated with fatigue. Numerous studies of individuals with negative mood status have shown significant positive response with 50-300 mg of 5-HTP daily   o further facilitate serotonin production, Thorne's 5-HTP formula contains pyridoxal 5'-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin. 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia. Directions Suggested Use: Take 1-3 capsule three times daily or as recommended by your healthcare practitioner. Free Of Gluten, dairy and soy. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Supplement Facts Serving Size: 2 Capsules Servings per Container: 45 Amount Per Serving% Daily Value Vitamin B6 (as Pyridoxal 5'-Phosphate)6.8 mg400% 5-Hydroxytryptophan100 mg Other Ingredients: Microcrystalline cellulose, hypromellose (dervied from cellulose) capsule, leucine, silicon dioxide. Warnings If pregnant, nursing or trying to conceive, consult your health-care practitioner before using this product. The product you receive may contain additional details or differ from what is shown on this page, or the product may have additional information revealed by partially peeling back the label. We recommend you reference the complete information included with your product before consumption and do not rely solely on the details shown on this page. For more information, please see our full disclaimer.